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Article

Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration

29 Nov 2016

Abstract excerpt

Age-related macular degeneration (AMD) is an eye disease underlined by the degradation of retinal pigment epithelium (RPE) cells, photoreceptors, and choriocapillares, but the exact mechanism of cell death in AMD is not completely clear. This mechanism is important for prevention of and therapeutic intervention in AMD, which is a hardly curable disease. Present reports suggest that both apoptosis and pyroptosis...

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PMID: 27900566
DOI: 10.1007/s10565-016-9371-8

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