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Article

Novel Programmed Cell Death as Therapeutic Targets in Age-Related Macular Degeneration?

1 Oct 2020

Abstract excerpt

Age-related macular degeneration (AMD) is a leading cause of severe visual loss among the elderly. AMD patients are tormented by progressive central blurring/loss of vision and have limited therapeutic options to date. Drusen accumulation causing retinal pigment epithelial (RPE) cell damage is the hallmark of AMD pathogenesis, in which oxidative stress and inflammation are the well-known molecular mechanisms....

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PMID: 33019767
DOI: 10.3390/ijms21197279

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