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Article

MTNR1B polymorphisms with CDKN2A and MGMT methylation status are associated with poor prognosis of colorectal cancer in Taiwan.

World journal of gastroenterology - 14 Sept 2021

Lee Chia-Cheng, Kuo Yu-Cheng, Hu Je-Ming, Chang Pi-Kai, Sun Chien-An, Yang Tsan, Li Chuan-Wang, Chen Chao-Yang, Lin Fu-Huang, Hsu Chih-Hsiung, Chou Yu-Ching

Abstract excerpt

BACKGROUND: Identifying novel colorectal cancer (CRC) prognostic biomarkers is crucial to helping clinicians make appropriate therapy decisions. Melatonin plays a major role in managing the circadian rhythm and exerts oncostatic effects on different kinds of tumours. AIM: To explore the relationship between MTNR1B single-nucleotide polymorphism (SNPs) combined with gene hypermethylation and CRC prognosis....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34629798
DOI: 10.3748/wjg.v27.i34.5737
PMCID: PMC8473598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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