Article
Genome-wide association studies may be misinterpreted: genes versus heritability.
Carcinogenesis - 1 Sept 2011
Vineis Paolo, Pearce Neil E
Abstract excerpt
Much of the literature on genome-wide association studies (GWAS) is based on the premise that an important proportion of common diseases is heritable and that this proportion is likely to be due to genetic variants detectable with extensive scans of the DNA. Heritability is estimated from family studies, including twin studies and is based on the comparison of the variation in disease among different members of...
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