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Article

Detection and interpretation of shared genetic influences on 42 human traits.

Nature genetics - 1 Jul 2016

Pickrell Joseph K, Berisa Tomaz, Liu Jimmy Z, Ségurel Laure, Tung Joyce Y, Hinds David A

Abstract excerpt

We performed a scan for genetic variants associated with multiple phenotypes by comparing large genome-wide association studies (GWAS) of 42 traits or diseases. We identified 341 loci (at a false discovery rate of 10%) associated with multiple traits. Several loci are associated with multiple phenotypes; for example, a nonsynonymous variant in the zinc transporter SLC39A8 influences seven of the traits, including...

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Identifiers

PMID: 27182965
DOI: 10.1038/ng.3570
PMCID: PMC5207801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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