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Rapid decline in vaccine-boosted neutralizing antibodies against SARS-CoV-2 Omicron variant

20 Jun 2022

Abstract excerpt

The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits reduced susceptibility to vaccine-induced neutralizing antibodies, requiring a boost to generate protective immunity. We assess the magnitude and short-term durability of neutralizing antibodies after homologous and heterologous boosting with mRNA and Ad26.COV2.S vaccines. All prime-boost combinations substantially...

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PMID: 35798000
DOI: 10.1016/j.xcrm.2022.100679

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