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Anti-SARS-CoV-2 receptor-binding domain antibody evolution after mRNA vaccination

7 Oct 2021

Abstract excerpt

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection produces B cell responses that continue to evolve for at least a year. During that time, memory B cells express increasingly broad and potent antibodies that are resistant to mutations found in variants of concern 1 . As a result, vaccination of coronavirus disease 2019 (COVID-19) convalescent individuals with currently available mRNA...

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PMID: 34619745
DOI: 10.1038/s41586-021-04060-7

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