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Article

A single-cell atlas of diffuse large B cell lymphoma

1 Apr 2022

Abstract excerpt

Diffuse large B cell lymphoma (DLBCL) is one of the most common yet aggressive types of B cell lymphoma and remains incurable in 40% of patients. Herein, we profile the transcriptomes of 94,324 cells from 17 DLBCLs and 3 control samples using single-cell RNA sequencing. Altogether, 73 gene expression programs are identified in malignant cells, demonstrating high intra- and intertumor heterogeneity. Furthermore,...

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PMID: 35443163
DOI: 10.1016/j.celrep.2022.110713

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