Effect of APOB polymorphism rs562338 (G/A) on serum proteome of coronary artery disease patients: a "proteogenomic" approach.

doi:10.1038/s41598-021-02211-4

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Article

Effect of APOB polymorphism rs562338 (G/A) on serum proteome of coronary artery disease patients: a "proteogenomic" approach.

Scientific reports - 23 Nov 2021

Zafar Muneeza, Mirza Munazza Raza, Awan Fazli Rabbi, Tahir Muhammad, Sultan Rabia, Hussain Misbah, Bilal Ahmed, Abbas Shahid, Larsen Martin R, Choudhary Muhammad Iqbal, Malik Imran Riaz

Abstract excerpt

In the current study, APOB (rs1052031) genotype-guided proteomic analysis was performed in a cohort of Pakistani population. A total of 700 study subjects, including Coronary Artery Disease (CAD) patients (n = 480) and healthy individuals (n = 220) as a control group were included in the study. Genotyping was carried out by using tetra primer-amplification refractory mutation system-based polymerase chain...

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PMID: 34815491
DOI: 10.1038/s41598-021-02211-4
PMCID: PMC8610978

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