Article
Strong association of the APOA5-1131T>C gene variant and early-onset acute myocardial infarction.
Atherosclerosis - 1 Feb 2011
De Caterina Raffaele, Talmud Philippa J, Merlini Piera Angelica, Foco Luisa, Pastorino Roberta, Altshuler David, Mauri Francesco, Peyvandi Flora, Lina Daniela, Kathiresan Sekar, Bernardinelli Luisa, Ardissino Diego
Abstract excerpt
BACKGROUND: Epidemiological studies support the role for a strong genetic component in the occurrence of early-onset myocardial infarction (MI), although the specific genetic variants responsible for familial clustering remain largely unknown. METHODS: The Italian study of early-onset MI is a nationwide case-control study involving 1864 case patients <45 years old who were hospitalized for a first MI, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.