Article
Single nucleotide polymorphisms in IL1B and the risk of acute coronary syndrome: a Danish case-cohort study.
PloS one - 1 Jan 2012
Stegger Jakob Gerhard, Schmidt Erik Berg, Tjønneland Anne, Kopp Tine Iskov, Sørensen Thorkild I A, Vogel Ulla, Overvad Kim
Abstract excerpt
BACKGROUND: Interleukin-1B (IL-1B) is a key pro-inflammatory cytokine that has been associated with the development of atherosclerosis and myocardial infarction. However, the prospective associations between functional single nucleotide polymorphisms (SNPs) in IL1B and incident acute coronary syndrome (ACS) have not been thoroughly investigated. The aims of this study were to examine the associations between...
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