Article
The APOB polymorphism rs1801701 A/G (p.R3638Q) is an independent risk factor for early-onset coronary artery disease: Data from a Spanish cohort.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 6 May 2021
Coto Eliecer, Lorca Rebeca, Rodríguez-Reguero Julián, Martín María, Pascual Isaac, Avanzas Pablo, Cuesta-Llavona Elías, Vázquez-Coto Daniel, Díaz-Corte Carmen, Tranche Salvador, Alonso Belén, Iglesias Sara, Morís César, Gómez Juan
Abstract excerpt
BACKGROUND AND AIMS: Apoliprotein B (ApoB) has been associated with hypercholesterolemia and ischemic coronary disease. This study was aimed to determine the effect of two APOB gene variants in the risk of developing early-onset coronary artery disease (EO-CAD) in a Spanish population. The association of these polymorphisms with hypercholesterolemia was also analysed. METHODS AND RESULTS: The study involved a...
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