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Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model

19 Apr 2022

Abstract excerpt

Dysfunctional immune responses contribute critically to the progression of Coronavirus Disease-2019 (COVID-19), with macrophages as one of the main cell types involved. It is urgent to understand the interactions among permissive cells, macrophages, and the SARS-CoV-2 virus, thereby offering important insights into effective therapeutic strategies. Here, we establish a lung and macrophage co-culture system...

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PMID: 35440562
DOI: 10.1038/s41467-022-29731-5

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