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Article

Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium.

Stem cell reports - 13 Jul 2021

Vaughan-Jackson Alun, Stodolak Szymon, Ebrahimi Kourosh H, Browne Cathy, Reardon Paul K, Pires Elisabete, Gilbert-Jaramillo Javier, Cowley Sally A, James William S

Abstract excerpt

Human induced pluripotent stem cells (iPSCs) and macrophages derived from them are increasingly popular tools for research into both infectious and degenerative diseases. However, as the field strives for greater modeling accuracy, it is becoming ever more challenging to justify the use of undefined and proprietary media for the culture of these cells. Here, we describe a defined, serum-free, open-source medium...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34171284
DOI: 10.1016/j.stemcr.2021.05.018
PMCID: PMC8282471

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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