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Article

Predicting Archaic Hominin Phenotypes from Genomic Data.

Annual review of genomics and human genetics - 31 Aug 2022

Brand Colin M, Colbran Laura L, Capra John A

Abstract excerpt

Ancient DNA provides a powerful window into the biology of extant and extinct species, including humans' closest relatives: Denisovans and Neanderthals. Here, we review what is known about archaic hominin phenotypes from genomic data and how those inferences have been made. We contend that understanding the influence of variants on lower-level molecular phenotypes-such as gene expression and protein function-is a...

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Identifiers

PMID: 35440148
DOI: 10.1146/annurev-genom-111521-121903
PMCID: PMC10250142

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