Article
The Genomic Health of Ancient Hominins.
Human biology - 1 Jan 2017
Berens Ali J, Cooper Taylor L, Lachance Joseph
Abstract excerpt
The genomes of ancient humans, Neandertals, and Denisovans contain many alleles that influence disease risks. Using genotypes at 3,180 disease-associated loci, we estimated the disease burden of 147 ancient genomes. After correcting for missing data, genetic risk scores (GRS) were generated for nine disease categories and the set of all combined diseases. We used these genetic risk scores to examine the effects...
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