Article
The genomic health of ancient hominins
2017-06-02
Abstract excerpt
The genomes of ancient humans, Neandertals, and Denisovans contain many alleles that influence disease risks. Using genotypes at 3180 disease-associated loci, we estimated the disease burden of 147 ancient genomes. After correcting for missing data, genetic risk scores were generated for nine disease categories and the set of all combined diseases. These genetic risk scores were used to examine the effects of diff...
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Identifiers and source
- Literature Corpus work
- d43ae2d6-bacf-52eb-a50f-d854de943bce
- DOI
- 10.1101/145193