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Article

Bicuspid aortic valve aortopathy: genetics, pathophysiology and medical therapy.

Interactive cardiovascular and thoracic surgery - 1 Sept 2013

Abdulkareem Nada, Smelt Jeremy, Jahangiri Marjan

Abstract excerpt

The association between ascending aortic aneurysm (AA) and bicuspid aortic valve (BAV) has been well established. Different genetic, haemodynamic and cardiovascular risk factors have been implicated in the development and progression of AA. However, to date, definite conclusions cannot be drawn regarding the exact molecular, cellular and haemodynamic mechanisms causing BAV-associated aortopathy. For this study,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23728086
DOI: 10.1093/icvts/ivt196
PMCID: PMC3745132

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