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Article

Hyper-Methylated Hub Genes of T-Cell Receptor Signaling Predict a Poor Clinical Outcome in Lung Adenocarcinoma

6 Apr 2022

Abstract excerpt

Background: Immune checkpoint inhibitors (ICIs) emerge as the first-line treatment of lung adenocarcinoma (LUAD); selection of subpopulations acquiring clinical benefit is required. Associations between epigenetic modulation of tumor microenvironment (TME) and clinical outcome are far from clear. We focused on immune-related genes closely regulated by DNA methylation to identify the potential clinical outcome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35432532
DOI: 10.1155/2022/5426887

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