Article

Identification of hub-methylated differentially expressed genes in lung adenocarcinoma and immunotherapy resistance

2022-11-30

Abstract excerpt

<title>Abstract</title><p>Incidence and mortality of lung adenocarcinoma are high, and the epigenetic mechanism of DNA methylation has a critical effect on LUAD at all stages. Our work used GEO and TCGA databases to identify differentially methylated genes (DMGs) in LUAD to explore how DNA methylation works in immunotherapy resistance. Candidate pathogenic genes were highly correlated to hub-methylated differentia...

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Literature Corpus work: 7b5c6912-6412-58f2-a87f-329674b19769
DOI: 10.21203/rs.3.rs-2317392/v1

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