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CCR2 and PTPRC are regulators of tumor microenvironment and potential prognostic biomarkers of lung adenocarcinoma

26 Aug 2021

Abstract excerpt

BACKGROUND: Tumor microenvironment (TME) plays an essential role in lung adenocarcinoma (LUAD) development and metastasis. With the development of TME research, it has been proved that differences in tumor-infiltrating immune cells (TICs) and gene expression profile are related to the prognosis of cancer. The aim of our study was to identify key genes affecting immune state in TME of LUAD. METHODS: The RNA-seq...

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Cancer Immunotherapy and Biomarkers
Chemokine receptors and signaling
Ferroptosis and cancer prognosis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34733971
DOI: 10.21037/atm-21-3301

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