Prognostic significance of the BAALC isoform pattern and CEBPA mutations in pediatric acute myeloid leukemia with normal karyotype: a study by the Japanese Childhood AML Cooperative Study Group.

doi:10.1007/s12185-010-0585-x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Prognostic significance of the BAALC isoform pattern and CEBPA mutations in pediatric acute myeloid leukemia with normal karyotype: a study by the Japanese Childhood AML Cooperative Study Group.

International journal of hematology - 1 Jun 2010

Mizushima Yasuhiro, Taki Tomohiko, Shimada Akira, Yui Yoshihiro, Hiraumi Yoshimi, Matsubara Hiroshi, Watanabe Motonobu, Watanabe Ken-ichiro, Kamitsuji Yuri, Hayashi Yasuhide, Tsukimoto Ichiro, Kobayashi Ryoji, Horibe Keizo, Tawa Akio, Nakahata Tatsutoshi, Adachi Souichi

Abstract excerpt

High BAALC (brain and acute leukemia, cytoplasmic) gene expression may indicate an adverse prognosis for adults who have acute myeloid leukemia (AML) and a normal karyotype, but its prognostic significance for pediatric AML cases is unclear. Whether different BAALC isoform patterns are of prognostic significance is also unclear. Newly diagnosed AML patients with normal karyotype who were treated by the Japanese...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CCAAT-Enhancer-Binding Proteins

Share to Gene Expression Regulation, Leukemic

Share to Infant, Newborn

Share to Karyotyping

Share to Leukemia, Myeloid, Acute

Share to Neoplasm Proteins

Share to Protein Isoforms

Source

Open in PubMed

Identifiers

PMID: 20495894
DOI: 10.1007/s12185-010-0585-x

Genes

BAALC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic significance of the BAALC isoform pattern and CEBPA mutations in pediatric acute myeloid leukemia with normal karyotype: a study by the Japanese Childhood AML Cooperative Study Group.PMID 20495894Read ↗

BAALC overexpression retains its negative prognostic role across all cytogenetic risk groups in acute myeloid leukemia patientsSemantic proximity Read ↗

BAALC gene expression tells a serious patient outcome tale in NPM1-wild type/FLT3-ITD negative cytogenetically normal-acute myeloid leukemia in adults.Semantic proximity Read ↗

BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study.Semantic proximity Read ↗

BAALC expression: a suitable marker for prognostic risk stratification and detection of residual disease in cytogenetically normal acute myeloid leukemiaSemantic proximity Read ↗

Prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia: a report from the Japanese Pediatric Leukemia/Lymphoma Study Group.Semantic proximity Read ↗

BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemiaSemantic proximity Read ↗

High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemiaSemantic proximity Read ↗

High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) studySemantic proximity Read ↗

CEBPA are independent good prognostic factors in pediatric acute myeloid leukemia.Semantic proximity Read ↗

Over expression of brain and acute leukemia, cytoplasmic and ETS-related gene is associated with poor outcome in acute myeloid leukemia.Semantic proximity Read ↗

Implication of higher BAALC expression in combination with other gene mutations in adult cytogenetically normal acute myeloid leukemia.Semantic proximity Read ↗

Clinical features, early treatment responses, and outcomes of pediatric acute lymphoblastic leukemia in china with or without specific fusion transcripts: A single institutional study of 1,004 patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.