Article
Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia.
Blood - 24 Nov 2011
Staffas Anna, Kanduri Meena, Hovland Randi, Rosenquist Richard, Ommen Hans Beier, Abrahamsson Jonas, Forestier Erik, Jahnukainen Kirsi, Jónsson Ólafur G, Zeller Bernward, Palle Josefine, Lönnerholm Gudmar, Hasle Henrik, Palmqvist Lars, Ehrencrona Hans
Abstract excerpt
Mutation status of FLT3, NPM1, CEBPA, and WT1 genes and gene expression levels of ERG, MN1, BAALC, FLT3, and WT1 have been identified as possible prognostic markers in acute myeloid leukemia (AML). We have performed a thorough prognostic evaluation of these genetic markers in patients with pediatric AML enrolled in the Nordic Society of Pediatric Hematology and Oncology (NOPHO) 1993 or NOPHO 2004 protocols....
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