Article
Clinical application of liquid biopsy in cancer patients.
BMC cancer - 15 Apr 2022
Chang Chieh-Min, Lin Kuei-Ching, Hsiao Nien-En, Hong Wei-An, Lin Chia-Yu, Liu Ta-Chih, Chang Ya-Sian, Chang Jan-Gowth
Abstract excerpt
BACKGROUND: This study was to determine the prevalence and clinical significance of clonal hematopoiesis (CH)-related variants, and somatic and germline mutations in cancer patients and healthy individuals. METHODS: We performed next-generation sequencing of 275 cancer-related genes be-tween plasma and white blood cells in 92 cancer patients and 47 controls without cancer. Blood samples were recruited from May...
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