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A Review of Circulating Tumor DNA (ctDNA) and the Liquid Biopsy in Cancer Diagnosis, Screening, and Monitoring Treatment Response

8 Apr 2025

Abstract excerpt

The concept of liquid biopsy is based on the knowledge that blood or secretions from the body contain tumor cells, nucleic acids, cellular components, and tumor metabolites. Detection of circulating DNA (ctDNA) in liquid biopsy material shows the most promise due to the advances in DNA technologies that have made detection and sample screening possible. Clinical trials have begun to evaluate ctDNA monitoring for...

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PMID: 40259565
DOI: 10.12659/msm.949300

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