Article
A Pilot Study Analyzing the Clinical Utility of Comprehensive Genomic Profiling Using Plasma Cell-Free DNA for Solid Tumor Patients in Japan (PROFILE Study).
Annals of surgical oncology - 1 Dec 2021
Matsudera Shotaro, Kano Yoshihito, Aoyagi Yasuko, Tohyama Kohki, Takahashi Kenta, Kumaki Yuichi, Mitsumura Takahiro, Kimura Koichiro, Onishi Iichiro, Takemoto Akira, Ban Daisuke, Ono Hiroaki, Kudo Atsushi, Oshima Noriko, Ogino Kei, Watanabe Shun, Tani Yukiko, Yamaguchi Takeshi, Nakajima Masanobu, Morita Shinji, Yamaguchi Satoru, Takagi Masatoshi, Ishikawa Toshiaki, Nakagawa Tsuyoshi, Okamoto Kentaro, Uetake Hiroyuki, Tanabe Minoru, Miyake Satoshi, Tsuchioka Takashi, Kojima Kazuyuki, Ikeda Sadakatsu
Abstract excerpt
BACKGROUND: The clinical utility of plasma cell-free DNA in precision cancer medicine has not been established. A pilot study was conducted to investigate the clinical utility of comprehensive genomic profiling by liquid biopsy in a Japanese population. METHODS: In this PROFILE study, 102 patients with advanced solid tumors who showed progression with standard systemic therapy underwent liquid biopsy between...
Topics
Join the communities discussing this publication.