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Article

Association between RAC1 gene variation, redox homeostasis and type 2 diabetes mellitus.

European journal of clinical investigation - 1 Aug 2022

Azarova Iuliia, Klyosova Elena, Polonikov Alexey

Abstract excerpt

BACKGROUND: Increased production of reactive oxygen species (ROS) and oxidative stress are known to play a key role in the pathogenesis of type 2 diabetes (T2D); however, the relationship between genes encoding a multi-subunit ROS-generated enzyme NADPH oxidase and disease susceptibility remains unexplored. AIMS: The present pilot study investigated whether single-nucleotide polymorphisms (SNP) at the RAC1 gene...

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Identifiers

PMID: 35416295
DOI: 10.1111/eci.13792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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