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Genetic interaction between oxidative stress and body mass index in a Spanish population.

Redox biology - 1 Mar 2025

Lara-Hernández Francisco, Melero Rebeca, Quiroz-Rodríguez María Elena, Moya-Valera Celeste, de Jesús Gallardo-Espinoza Mariana, Álvarez Luis, Valarezo-Torres Ingrid Lizeth, Briongos-Figuero Laisa, Abadía-Otero Jessica, Mena-Martin Francisco Javier, Saez Guillermo, Redon Josep, Martín-Escudero Juan-Carlos, García-García Ana-Bárbara, Ayala Guillermo, Chaves Felipe Javier

Abstract excerpt

Oxidative stress may act as a contributing factor in the development of an elevated body mass index (BMI). Oxidative stress has the potential to modulate genetic activity at various levels, including gene transcription and protein function regulation. Nevertheless, the interplay between genetic variants and oxidative stress in relation to BMI remains to be elucidated. Based on this premise, we studied the...

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8-Hydroxy-2'-Deoxyguanosine
Aged
Body Mass Index
Malondialdehyde

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oxidative Stress

Polymorphism, Single Nucleotide

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Open in PubMed Open full text

Identifiers

PMID: 39923398
DOI: 10.1016/j.redox.2025.103531
PMCID: PMC11849672

Genes

CPT1A
DDIT3
IL6ST
NPPA
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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