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Article

The possible role of 10398A and 16189C mtDNA variants in providing susceptibility to T2DM in two North Indian populations: a replicative study.

Human genetics - 1 Feb 2007

Bhat Audesh, Koul Anil, Sharma Swarkar, Rai Ekta, Bukhari S I A, Dhar M K, Bamezai R N K

Abstract excerpt

The role of mitochondria in causing diseases is becoming evident as more and more studies are focusing on this organelle of the cell. This is largely attributed to its reactive oxygen species (ROS) production property. In the context of diabetes, ROS is suggested to trigger different forms of insulin resistance involving different mechanisms. The suggestive role of a mtDNA variant G10398A in increasing ROS...

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Identifiers

PMID: 17066297
DOI: 10.1007/s00439-006-0272-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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