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Article

Expanded COVID-19 phenotype definitions reveal distinct patterns of genetic association and protective effects.

Nature genetics - 1 Apr 2022

Roberts Genevieve H L, Partha Raghavendran, Rhead Brooke, Knight Spencer C, Park Danny S, Coignet Marie V, Zhang Miao, Berkowitz Nathan, Turrisini David A, Gaddis Michael, McCurdy Shannon R, Pavlovic Milos, Ruiz Luong, Sass Chodon, Haug Baltzell Asher K, Guturu Harendra, Girshick Ahna R, Ball Catherine A, Hong Eurie L, Rand Kristin A

Abstract excerpt

Multiple COVID-19 genome-wide association studies (GWASs) have identified reproducible genetic associations indicating that there is a genetic component to susceptibility and severity risk. To complement these studies, we collected deep coronavirus disease 2019 (COVID-19) phenotype data from a survey of 736,723 AncestryDNA research participants. With these data, we defined eight phenotypes related to COVID-19...

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Source

Identifiers

PMID: 35410379
DOI: 10.1038/s41588-022-01042-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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