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Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity.

Nature genetics - 1 Jun 2021

Shelton Janie F, Shastri Anjali J, Ye Chelsea, Weldon Catherine H, Filshtein-Sonmez Teresa, Coker Daniella, Symons Antony, Esparza-Gordillo Jorge, Aslibekyan Stella, Auton Adam

Abstract excerpt

COVID-19 presents with a wide range of severity, from asymptomatic in some individuals to fatal in others. Based on a study of 1,051,032 23andMe research participants, we report genetic and nongenetic associations with testing positive for SARS-CoV-2, respiratory symptoms and hospitalization. Using trans-ancestry genome-wide association studies, we identified a strong association between blood type and COVID-19...

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PMID: 33888907
DOI: 10.1038/s41588-021-00854-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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