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Article

Association of KMT2C Genetic Variants with the Clinicopathologic Development of Oral Cancer.

International journal of environmental research and public health - 27 Mar 2022

Shieu Mu-Kuei, Ho Hsin-Yu, Lin Shu-Hui, Lo Yu-Sheng, Lin Chia-Chieh, Chuang Yi-Ching, Hsieh Ming-Ju, Chen Mu-Kuan

Abstract excerpt

Lysine methyltransferase 2C (KMT2C) is a tumor-suppressor gene in several myeloid cells and epithelia and is linked with blood and solid tumor cancers. KMT2C single-nucleotide polymorphisms (SNPs) are also connected with several cancer types. Our study aimed to explore the potential genetic polymorphisms of KMT2C in oral cancer. Five KMT2C SNPs, including rs201834857, rs4725443, rs6464221, rs74483926, and...

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Share to Carcinoma, Squamous Cell
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Identifiers

PMID: 35409657
DOI: 10.3390/ijerph19073974
PMCID: PMC8997509

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