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Article

KMT2C, a histone methyltransferase, is mutated in a family segregating non-syndromic primary failure of tooth eruption.

Scientific reports - 11 Nov 2019

Assiry Ali A, Albalawi Alia M, Zafar Muhammad S, Khan Siraj D, Ullah Anhar, Almatrafi Ahmed, Ramzan Khushnooda, Basit Sulman

Abstract excerpt

Primary failure of tooth eruption (PFE) is a rare odontogenic defect and is characterized by failure of eruption of one or more permanent teeth. The aim of the study is to identify the genetic defect in a family with seven affected individuals segregating autosomal dominant non-syndromic PFE. Whole genome single-nucleotide polymorphism (SNP) genotyping was performed. SNP genotypes were analysed by DominantMapper...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31712638
DOI: 10.1038/s41598-019-52935-7
PMCID: PMC6848163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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