Article
Polygenic and Network-based studies in risk identification and demystification of cancer.
Expert review of molecular diagnostics - 1 Apr 2022
El Hadi Christopher, Ayoub Georges, Bachir Yara, Haykal Michèle, Jalkh Nadine, Kourie Hampig Raphael
Abstract excerpt
INTRODUCTION: Diseases were initially thought to be the consequence of a single gene mutation. Advances in DNA sequencing tools and our understanding of gene behavior have revealed that complex diseases, such as cancer, are the product of genes cooperating with each other and with their environment in orchestrated communication networks. Seeing that the function of individual genes is still used to analyze...
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