Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical implementation of polygenic risk scores

29 Sept 2025

Abstract excerpt

Risk of a disease is not binary but a continuum. The difficulty in ascertaining an individual’s risk is further complicated as it is almost always multifactorial and will evolve over time. While stratified screening exists in certain diseases for higher risk individuals, this is frequently based on outdated and simplistic criteria. Accurate risk estimation is essential for medical professionals to give fully...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Associations and Epidemiology
Share to Genetic factors in colorectal cancer
Share to Liver Disease Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 41023409
DOI: 10.1038/s41431-025-01931-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical implementation of polygenic risk scoresPMID 41023409Read ↗

Opportunities and Challenges for Polygenic Risk Scores in Prognostication and Prevention of Cardiovascular Disease.Semantic proximity Read ↗

Polygenic risk scores: improving the prediction of future disease or added complexity?Semantic proximity Read ↗

Clinical utility and implementation of polygenic risk scores for predicting cardiovascular disease: A clinical consensus statement of the ESC Council on Cardiovascular Genomics, the ESC Cardiovascular Risk Collaboration, and the European Association of Preventive CardiologySemantic proximity Read ↗

How Do We Incorporate Polygenic Risk Scores in Cardiovascular Disease Risk Assessment and Management?Semantic proximity Read ↗

A perspective on genetic and polygenic risk scores-advances and limitations and overview of associated tools.Semantic proximity Read ↗

Untitled literature recordSemantic proximity Read ↗

Polygenic Risk Scores: What Are They Good For?Semantic proximity Read ↗

Polygenic Risk Scores in Human Disease.Semantic proximity Read ↗

Polygenic risk scores for CARDINAL study.Semantic proximity Read ↗

[Interest in the use of polygenic risk scores in breast cancer screening and preventive medicine].Semantic proximity Read ↗

Improving reporting standards for polygenic scores in risk prediction studies.Semantic proximity Read ↗

Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.