Protective HLA alleles against severe COVID-19: HLA-A*68 as an ancestral protection allele in Tapachula-Chiapas, Mexico.

doi:10.1016/j.clim.2022.108990

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Protective HLA alleles against severe COVID-19: HLA-A*68 as an ancestral protection allele in Tapachula-Chiapas, Mexico.

Clinical immunology (Orlando, Fla.) - 1 May 2022

Hernández-Doño Susana, Sánchez-González Roberto Alejandro, Trujillo-Vizuet Ma Guadalupe, Zamudio-Castellanos Fabiola Yeseline, García-Silva Rafael, Bulos-Rodríguez Pedro, Vazquez-Guzmán Carlos A, Cárdenas-Ramos Ximena, de León Rodríguez Diana, Elías Fabiola, Domínguez-Arrevillaga Sergio, Pérez-Tirado José Manuel, Vera-Lastra Olga Lidia, Granados Julio, Sepúlveda-Delgado Jesús

Abstract excerpt

HLA is a polymorphic antigen presenter which has provided valuable information on the susceptibility of populations to viruses. Therefore, the study of HLA can reveal specific susceptibility or resistance alleles to severe COVID-19 in an ethnically dependent manner. This pilot study investigated HLA alleles associated with COVID-19 severity in Tapachula, Chiapas, Mexico. A total of 146 Mexican Mestizos were typed...

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Identifiers

PMID: 35395388
DOI: 10.1016/j.clim.2022.108990
PMCID: PMC8982524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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