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Article

Association between HLA-C alleles and COVID-19 severity in a pilot study with a Spanish Mediterranean Caucasian cohort.

PloS one - 1 Jan 2022

Vigón Lorena, Galán Miguel, Torres Montserrat, Martín-Galiano Antonio J, Rodríguez-Mora Sara, Mateos Elena, Corona Magdalena, Malo Rosa, Navarro Cristina, Murciano-Antón María Aránzazu, García-Gutiérrez Valentín, Planelles Vicente, Martínez-Laso Jorge, López-Huertas María Rosa, Coiras Mayte

Abstract excerpt

The clinical presentations of COVID-19 may range from an asymptomatic or mild infection to a critical or fatal disease. Several host factors such as elderly age, male gender, and previous comorbidities seem to be involved in the most severe outcomes, but also an impaired immune response that causes a hyperinflammatory state but is unable to clear the infection. In order to get further understanding about this...

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Identifiers

PMID: 35960731
DOI: 10.1371/journal.pone.0272867
PMCID: PMC9374209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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