Article
High-throughput and efficient multilocus genome-wide association study on longitudinal outcomes.
Bioinformatics (Oxford, England) - 1 May 2020
Xu Huang, Li Xiang, Yang Yaning, Li Yi, Pinheiro Jose, Sasser Kate, Hamadeh Hisham, Steven Xu, Yuan Min
Abstract excerpt
MOTIVATION: With the emerging of high-dimensional genomic data, genetic analysis such as genome-wide association studies (GWAS) have played an important role in identifying disease-related genetic variants and novel treatments. Complex longitudinal phenotypes are commonly collected in medical studies. However, since limited analytical approaches are available for longitudinal traits, these data are often...
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