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Article

FastBiCmrMLM: a fast and powerful compressed variance component mixed logistic model for big genomic case-control genome-wide association study.

Briefings in bioinformatics - 23 May 2024

Wang Jing-Tian, Chang Xiao-Yu, Zhao Qiong, Zhang Yuan-Ming

Abstract excerpt

Large sample datasets have been regarded as the primary basis for innovative discoveries and the solution to missing heritability in genome-wide association studies. However, their computational complexity cannot consider all comprehensive effects and all polygenic backgrounds, which reduces the effectiveness of large datasets. To address these challenges, we included all effects and polygenic backgrounds in a...

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Identifiers

PMID: 38888457
DOI: 10.1093/bib/bbae290
PMCID: PMC11184901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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