Article
Treatment of Thoracic SMARCA4-Deficient Undifferentiated Tumors: Where We Are and Where We Will Go.
International journal of molecular sciences - 13 Mar 2024
Longo Vito, Catino Annamaria, Montrone Michele, Montagna Elisabetta Sara, Pesola Francesco, Marech Ilaria, Pizzutilo Pamela, Nardone Annalisa, Perrone Antonella, Gesualdo Monica, Galetta Domenico
Abstract excerpt
Recently, the fifth edition of the WHO classification recognized the thoracic SMARCA4-deficient undifferentiated tumor (SMARCA4-UT) as a separate entity from conventional non-small cell lung cancer with SMARCA4 deficiency because of the different clinicopathological characteristics of these two diseases. SMARCA4-UT mainly occurs in young to middle-aged adults and involves a large mass compressing the tissues...
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