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Article

Epigenetics in Congenital Heart Disease.

Journal of the American Heart Association - 5 Apr 2022

Wang Guanglei, Wang Bingbing, Yang Peixin

Abstract excerpt

Embryonic heart development is an intricate process that mainly involves morphogens, transcription factors, and cardiac genes. The precise spatiotemporal expression of these genes during different developmental stages underlies normal heart development. Thus, mutation or aberrant expression of these genes may lead to congenital heart disease (CHD). However, evidence demonstrates that the mutation of genes...

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Identifiers

PMID: 35348004
DOI: 10.1161/JAHA.121.025163
PMCID: PMC9075469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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