[Research progress on genetic and epigenetic mechanisms in congenital heart disease].

Abstract excerpt

Congenital heart disease (CHD) is a type of birth defects due to the abnormal development of heart and blood vessels during embryonic stage. Studies indicate that the etiology of CHD is complicated. Genetic and epigenetic mechanisms including chromosomal abnormalities, gene mutations, nucleic acid modifications, non-coding RNAs may play important roles in CHD. At present, genetic mechanisms such as chromosome...

Topics

• Chromosome Aberrations
• DNA Copy Number Variations
• Epigenesis, Genetic
• Heart Defects, Congenital
• Humans
• Mutation