Role of Epigenetics in Cardiac Development and Congenital Diseases

doi:10.1152/physrev.00048.2017

Article

Role of Epigenetics in Cardiac Development and Congenital Diseases

29 Aug 2018

Abstract excerpt

The heart is the first organ to be functional in the fetus. Heart formation is a complex morphogenetic process regulated by both genetic and epigenetic mechanisms. Congenital heart diseases (CHD) are the most prominent congenital diseases. Genetics is not sufficient to explain these diseases or the impact of them on patients. Epigenetics is more and more emerging as a basis for cardiac malformations. This review...

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