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Epigenetics and Mechanobiology in Heart Development and Congenital Heart Disease

1 Sept 2019

Abstract excerpt

Congenital heart disease (CHD) is the most common birth defect worldwide and the number one killer of live-born infants in the United States. Heart development occurs early in embryogenesis and involves complex interactions between multiple cell populations, limiting the understanding and consequent treatment of CHD. Furthermore, genome sequencing has largely failed to predict or yield therapeutics for CHD. In...

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PMID: 31480510
DOI: 10.3390/diseases7030052

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