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Article

Genetic factors associated with drug-resistance of epilepsy: relevance of stratification by patient age and aetiology of epilepsy.

Seizure - 1 Mar 2010

Sánchez M Blanca, Herranz José L, Leno Carlos, Arteaga Rosa, Oterino Agustín, Valdizán Elsa M, Nicolás José M, Adín Javier, Armijo Juan A

Abstract excerpt

Epilepsy drug-resistance may depend on the metabolism of antiepileptic drugs (AEDs), transport to the epileptic focus and/or target sensitivity. Furthermore, drug response depends on multiple characteristics of the patient, the epilepsy, and the antiepileptic drugs used. We have investigated the association between polymorphisms related to antiepileptic drug metabolism (CYP2C9, CYP2C19, and UGT), transport...

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Source

Identifiers

PMID: 20064729
DOI: 10.1016/j.seizure.2009.12.004

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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