Article
Genetic associations in chronic hepatitis B infection: toward developing polygenic risk scores.
Future microbiology - 1 May 2022
Tandoh Kwesi Z, Quaye Osbourne
Abstract excerpt
Chronic hepatitis B (CHB) infection results in multiple clinical phenotypes of varying severity. One of the critical gaps in CHB management is the lack of a genetic-based tool to aid existing hepatocellular carcinoma and cirrhosis risk stratification models for patients with active CHB. Such individual predictive models for CHB are plagued by an inherent limitation of discriminatory power that clearly...
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