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Article

HLA class I allelic diversity and progression of fibrosis in patients with chronic hepatitis C.

Hepatology (Baltimore, Md.) - 1 Feb 2006

Patel Keyur, Norris Suzanne, Lebeck Lauralynn, Feng Anne, Clare Michael, Pianko Stephen, Portmann Bernard, Blatt Lawrence M, Koziol James, Conrad Andrew, McHutchison John G

Abstract excerpt

Patients infected with HIV-1 who are heterozygous at HLA class I loci present greater variety of antigenic peptides to CD8+ cytotoxic T lymphocytes, slowing progression to AIDS. A similar broad immune response in chronic hepatitis C (CHC) infection could result in greater hepatic injury. Although...

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PMID: 16440356
DOI: 10.1002/hep.21040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16440356-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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