Article
Understanding the host genetics of chronic hepatitis B and C.
Seminars in liver disease - 1 May 2011
Thursz Mark, Yee Leland, Khakoo Salim
Abstract excerpt
The outcome of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are heterogeneous, ranging from an asymptomatic self-limiting infection to cirrhosis and hepatocellular carcinoma. Several viral environmental and demographic variables have been identified as determinants of disease outcome, but these fail to explain a large proportion of the variability. Evidence from twin studies suggests that the...
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