Article
DCHap: A Divide-and-Conquer Haplotype Phasing Algorithm for Third-Generation Sequences.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Li Yanbo, Lin Yu
Abstract excerpt
The development of DNA sequencing technologies makes it possible to obtain reads originated from both copies of a chromosome (two parental chromosomes, or haplotypes) of a single individual. Reconstruction of both haplotypes (i.e., haplotype phasing) plays a crucial role in genetic analysis and provides relationship information between genetic variation and disease susceptibility. With the emerging...
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