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Attempting to Solve the Pigmented Epithelioid Melanocytoma (PEM) Conundrum

22 Mar 2022

Abstract excerpt

Pigmented epithelioid melanocytoma is a rare cutaneous melanocytic proliferation considered high-grade melanocytoma in the 2018 WHO Classification of Skin Tumors. Little has been reported about the associated genetic drivers in addition to BRAF and MAP2K1 mutations or PRKCA gene fusions. Here, we present a series of 21 cases of PRKAR1A -inactivated melanocytic tumors in which we could assess the associated...

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Share to Cutaneous Melanoma Detection and Management
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PMID: 35319526
DOI: 10.1097/pas.0000000000001888

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